Alias got two of the recommendations right.

As for the Slav, it's going to be as main line as it gets, since the Semi-Slav is going straight down 5. Bg5. The Slav is a great opening, and, for example, I briefly mention the variations that put me off from recommending the fashionable 4. Qc2 with e3/Rd1 before Nc3 idea, and the Avrukh approach to the Slow Slav.
As for differences from the Khalifman series, just for an idea: part one of the book covers dark-squared defenses (Grunfeld, KID, Old Indian, Pirc/Modern, 1...d6) and there's very significant differences in choices (even the Old Indian chapter is appreciably different, with attention paid to the recent "The New Old Indian" recommendation), with explanations of why when possible.
I'm doing my best to ensure recent material on openings I cover is mentioned, for example "The Safest Grunfeld" recommendation is covered, and improved upon for white.
Best of luck, BPaulsen. Really curious to read this - it sounds great!