Saubhikr,
After ..g6, play transposes to the Closed Gruenfeld (D94). In this variation, the middlegame play tends to be of the subtle, positional type. As White, you want to do a bit of patient maneuvering with the aim of reaching a favorable ending. If this doesn't fit your style or if your endgame skills aren't up to the task, then you might do better with another variation.
Here is a little test to help you decide:
White to move. OK, now, first impression -- quick look without using a database or an engine -- what do you think of this position?
[scroll down for answer]
If you look at this position and your initial instinct is to think that its boring or equal, then perhaps a different variation is in order. (No worries, that would have been my first inclination too!). But if this sort of position causes you to start salivating at the prospect of a win, then you should have no problem with 4.e3 g6.
Indeed, despite the limited amount of material and the opposite colored bishops, a close look reveals that White is significantly better here. His bishop is much stronger than its Black counterpart, and the pawns on e4 and f7 are subject to attack. Magnus Carlsen went on to win this position in instructive fashion as White against Bu Xiangzhi, Biel 2007.
From the diagram, play continued: 32. Bb3 b6 33. Rd7 (forcing the black rook to a passive position on f8 -- I love how Magnus improves his position before rounding up the e4 pawn) 33... Rf8 34. g4 g5 35. Rb7 Bc5 36. Bd5 Kg7 37. Kf1 h6 38. Ke2 Kf6 39. a4 Kg7 40. Rc7 Bb4 41. Bxe4 (finally) Rd8 42. Bd3 Kf8 43. Rb7 Rd6 44. Bc4 Rf6 45. Bd5 Be7 46. f3 Bb4 47. Kd3 Be1 48. Ke4 Bg3 49. Bc4 Be1 50. f4 gxf4 51. exf4 Bg3 52. f5 Be1 53. Bd5 Kg7 54. Kd4 h5 55. Kc4 hxg4 56. hxg4 Bf2 57. Be6 Be3 58. Kd5 Kf8 59. Ke5 Kg7 60. Ke4 Bd2 61. Kd3 Bf4 62. Kc4 Kf8 63. Bd5 Be3 64. Kb5 Kg7 65. Be6 Kf8 66. Bc4 Bf2 67. Bd5 Kg7 68. Bc6 Kh6 69. Rxb6 (this is a typical idea in these endings, the superior side offers to sack the exchange in order to get a passed pawn) 69..Kg5 70. a5 Rd6 71. Rb7 Kxg4 72. Rxf7 Kg5 73. Rd7 Rh6 74. Be4 Rh8 75. a6 Rb8+ 76. Kc4 Kf4 77. Re7 Rc8+ 78. Kd3 Rd8+ 79. Ke2 Bd4 80. Bd3 Bc5 81. Re6 Rh8 82. f6 Rh2+ 83. Kd1 Rh6 84. f7 1-0
Bravo!