There really is no "safe" line in the Grunfeld that will give White an advantage.
I am a "Former" 1.d4 player, and against the Grunfeld, I've always found the following line to work best, but if Black knows the line, he can get equality out of it (though White's king is "FAIRLY" safe).
1.d4 Nf6 2.c4 g6 3.Nc3 d5 4.cxd5 Nxd5 5.e4 Nxc3 6.bxc3 Bg7 (Or Black can play 6...c5. In this line, basically Black's moves 6-9 involve ...c5, ...Nc6, ...Bg7, and ...0-0, though order really isn't important here) 7.Bc4 c5 8.Ne2 Nc6 9.Be3 0-0 10.Rc1 cxd4 11.cxd4 Qa5+ 12.Kf1 and now 12...Qa3! Gives Black full equality as White can't play f3 due to the loose bishop on e3 then. Therefore ...Bg4 is a threat. In response, White should play 13.Qb3, when Black has the choice between the rare 13...Qd6, or the most common, 13...Qxb3. Play is equal, but the Queens are gone, and the attack is therefore reduced.
Now many players aren't familiar with the line, and don't play 12...Qa3. Against moves like say, 12...Bd7, White starts using the h-file for an attack. 13.h4! intending h5 and hxg6. This is not a very good plan if the Queens are gone, but otherwise, this attack can often be lethal for Black. I actually just started taking up the Grunfeld again as Black, and I can tell you that against me, you'd get 12...Qa3, since I obviously know the correct line of play for Black.
But as your other responder said, the Grunfeld is dynamic. You can't play a "Safe" line against the Grunfeld and expect any advantage.
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